Oxymetholone 10mg

Product desciption

Oxymetholone is produced in tablet form and contains the active substance Oxymetholone – a potent anabolic steroid, that enhances protein synthesis, stimulates the production of erythropoietin, activates hematopoiesis (blood formation).

Oxymetholone is used to treat the symptoms of anemia caused by deficient red cell production. Congenital aplastic anemia, acquired aplastic anemia, myelofibrosis, and hypoplastic anemias due to the administration of myelotoxic drugs often respond. The usage of this drug leads to increased hemoglobin synthesis. Oxymetholone should not replace other supportive measures such as correction of iron, folic acid, vitamin B12, transfusion, antibacterial therapy, and the appropriate use of corticosteroids.

The drug should not be taken by patients who have the following contraindications:

• Prostate cancer.
• Male breast cancer.
• Breast cancer in females with hypercalcemia.
• Pregnancy and lactation. Women who are planning or may.
• Become pregnant should not use this drug, it can harm the fetus.
• The nephrotic phase of nephritis or nephrosis.
• Severe hepatic dysfunction.
• Severe kidney disease.
• Hypersensitivity to the drug.

Dosage and side effects

The recommended daily dose in adults is 1-5 mg/kg of body weight per day. Usually, dosages of 1-2 mg/kg/day are sufficient for effective treatment, higher doses are selected individually.

Dose selection for elderly patients should be cautious, usually starting at the low end of the dosing range.

The duration of the course is up to 6 months. The response of the use of Oxymetholone is not often immediate and may be noticeable after 3-6 months. Following remission, some patients may be maintained without the drug, others may need to use a lower daily dose. Patients with congenital aplastic anemia usually require a continued maintenance dose

Like all medicines, Oxymetholone can cause side effects. The following adverse reactions may occur both in men and women: 1. Cholestatic jaundice with, rarely, hepatic necrosis and death. There are reports of hepatocellular neoplasms and peliosis of the liver in association with long-term anabolic steroid therapy.
2. Bleeding in patients on concomitant anticoagulant therapy, iron-deficiency anemia.
3. Risk of developing leukemia (see CARCINOGENESIS).
4. Nausea, vomiting, diarrhea.
5. Excitement, insomnia.
6. Decreased or increased libido.
7. Fertility disorders.
8. Hirsutism and male-pattern baldness in women, male-pattern of hair loss in mеn.
9. Acne (mostly in women and prepubertal boys).
10. Premature closure of epiphyses in children (see PRECAUTIONS), muscle cramps.
11. Edema.
12. Chills.
13. Increased excretion of creatine and creatinine, increased serum levels of creatinine phosphokinase (CPK). Reversible changes in liver function tests may be observed, including increased Bromsulphalein (BSP) retention and increases in serum bilirubin, glutamine oxaloacetic transaminase (SGOT), and alkaline phosphatase.
Side effects that occur in men:
14. Gynecomastia.
15. Phallic enlargement and increased frequency of erections.
16. Testicular atrophy, oligospermia.
17. Impotence.
18. Chronic priapism.
19. Inhibition of testicular function.
20. Epididymitis.
21. Bladder irritability and decrease in seminal volume. Women may have signs of virilization.
22. Deepening of the voice.